Introduction to Dry Granulation Dry granulation is a tablet manufacturing process used to convert fine powder into granules without using any liquid binder. This makes it especially useful for moisture-sensitive and heat-sensitive drugs. In pharmaceutical production, granulation improves powder flow, content uniformity, and compressibility — all essential for making high-quality tablets. While wet granulation process […]
Introduction The diagram below provides a simplified overview of the complete wet granulation process in pharmaceutical manufacturing. Wet granulation is one of the most widely used processes in pharmaceutical tablet manufacturing. If you visit any solid dosage manufacturing facility, chances are that most tablet products are made using this method. It is especially useful when
In the pharmaceutical industry, even a small change can affect product quality, safety, and regulatory compliance. That’s why companies follow a Change Control Procedure — a formal system to evaluate, approve, implement, and document changes in a controlled manner. Change control is not just paperwork. It is a GMP requirement that ensures any change made
Introduction Tablet manufacturing is one of the most common and important processes in the pharmaceutical industry. Tablets are widely used because they are easy to administer, stable, and cost-effective. However, making a tablet is not just mixing powders and compressing them — it is a highly controlled GMP process where every step affects product quality,
Tablet manufacturing is one of the most common processes in the pharmaceutical industry. But before tablets are compressed, powders must be converted into a form that flows well and compresses properly. This important step is called granulation. In this article, we will understand the granulation process in tablet manufacturing, why it is needed, types of
Introduction In the pharmaceutical industry, the warehouse is the first control point for incoming raw materials, packaging materials, and other supplies. A proper material receipt procedure in pharmaceutical ensures that only the correct and approved materials enter the facility. This process is very important for maintaining product quality, GMP compliance, and patient safety. If materials
Introduction In the pharmaceutical industry, a pharmaceutical warehouse is not just a storage place — it is a critical control point for product quality and regulatory compliance. A well-designed warehouse layout ensures that raw materials, packing materials, and finished goods are stored under controlled conditions, preventing mix-ups, contamination, and errors. According to Good Manufacturing Practices
Introduction to GMP in Pharmaceuticals Good Manufacturing Practices (GMP) are the backbone of the pharmaceutical industry. GMP in Pharmaceuticals is a system that ensures medicines are consistently produced and controlled according to quality standards. These guidelines are designed to minimize risks involved in pharmaceutical production that cannot be eliminated through testing the final product alone.
Introduction The Batch Manufacturing Record (BMR) is one of the most critical documents in the pharmaceutical manufacturing process. It provides complete and traceable evidence that a batch has been manufactured, processed, and controlled in accordance with approved procedures and Good Manufacturing Practices (GMP). In pharmaceutical industries, no batch is considered complete or releasable without a
Introduction Line clearance is one of the most critical Good Manufacturing Practice (GMP) activities in pharmaceutical manufacturing. It is performed to ensure that no materials, documents, labels, or products from the previous batch remain on the production or packaging line before starting a new batch or product.Proper line clearance helps prevent mix-ups, cross-contamination, and serious
